That size tire will fit fine, not sure if the spacer will cause a problem or not. Sometimes the use of spacers requires the modification of the pinch seam. As puddlesplasher said, check with IDoMyOwnRacing.
Welcome to the forum. There is a lot of great info on this forum. You will not have any problem with the 225/65/17 on your Latitude. Enjoy your new Latitude.Let me know I just bought a 2020 Jeep Renegade latitude with 17x 7 rims. I was looking at the 225/65R17 tires as well.