I doubt you could open it all the way. The end of the tailgate is more than 16 inches higher than the roof. If the side rails are 2.5 inches high, and your cross bars are another 1.5 inches higher than that, you still have a foot of tailgate in the way. You may be able to open it partially depending on how high your cross bars are. Note that the antenna sticks up quite a bit too, but can be easily unscrewed.